Analysis of Monoclonal Antibody Digests with the Agilent 1290 Infinity 2D-LC Solution

contributed by Agilent Technologies | 02/18/2014

Protein biopharmaceuticals such as monoclonal antibodies and recombinant proteins are currently in widespread use for the treatment of various life-threatening diseases including cancer and autoimmune diseases. Protein therapeutics have a complexity far exceeding that of small molecule drugs, hence, unraveling this complexity represents an analytical challenge.

This Application Note demonstrates the potential of comprehensive two-dimensional liquid chromatography (LCxLC) using the Agilent 1290 Infinity 2D-LC Solution with DAD detection for the analysis of monoclonal antibody tryptic digests.

Log in or register to read this article in full and gain access to The Analytical Scientist’s entire content archive. It’s FREE!

Email*

Choose a password

I have read and understand the Privacy Notice *

Stay up to date with our other newsletters and sponsors information, tailored specifically to the fields you are interested in

Receive communication from The Cannabis Scientist I want to stay up to date with the Mass Spectrometry field I want to stay up to date with the Spectroscopy field

When you click “Subscribe” we will email you a link, which you must click to verify the email address above and activate your subscription. If you do not receive this email, please contact us at [email protected].
If you wish to unsubscribe, you can update your preferences at any point.