Analysis of THC and an Extended Metabolite Suite from Oral Fluid
contributed by Biotage |
Analysis of THC and an Extended Metabolite Suite from Oral Fluid Using ISOLUTE® SLE+ Supported Liquid Extraction Columns Prior to LC-MS/MS
Introduction
The method described in this application note achieves high recoveries of THC and an extended suite of common metabolites in oral fluid from Quantisal (Immunalysis) oral fluid collection devices.
ISOLUTE® SLE+ products provide clean, rapid, robust, efficient , high throughput and automatable extraction solutions for a wide range of analytes.
This application note describes effective and efficient ISOLUTE SLE+ protocols optimized for sample loading volumes of either 300 μL or 800 μL. The simple sample preparation procedure delivers clean extracts and analyte recoveries greater than 64% with RSDs of <10% for allanalytes.
Log in or register to read this article in full and gain access to The Analytical Scientist’s entire content archive. It’s FREE!