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Better Gel Filtration: A New Look at Method Development Parameters Using Yarra™ GFC Columns

Summary

An affordable, high efficiency Yarra GFC column was recently introduced and is significantly more efficient than other GFC columns on the market. In addition to higher efficiency, Yarra columns demonstrate significantly higher inertness to ionic interactionsversus other GFC columns; however, such chemical characteristics require optimization to operating parameters. In particular, salt and buffer concentration can have a significant impact on secondary interactions which can influence GFC separations. Performing method development through mobile phase composition using next-generation Yarra GFC columns will be discussed.

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