Chemical Characterization of Pharmaceutical Samples by Confocal Raman Microscopy and Correlative Techniques

Introduction

Development, production and quality control in the pharmaceutical industry requires efficient and reliable control mechanisms to ensure the safety and therapeutic effect of the final products. These products can vary widely in composition and application. Several of their properties can be difficult to study with conventional techniques due to the inability of these methods to chemically differentiate materials with sufficient spatial resolution and without damage or staining. Therefore analyzing methods that provide both comprehensive chemical characterization and the flexibility to adjust the method to the investigated specimen are preferred in pharmaceutical research.