Complex mixture analysis using Hydrogen

contributed by Peak Scientific | 07/08/2014

This technical brief aims to demonstrate the performance of GC-MS using hydrogen carrier gas. Here we compare the performance of hydrogen and helium for the analysis of a complex mixture. Results show that by using hydrogen, chromatographers can achieve superior results to helium, with faster run times and taller, sharper peaks.

Owing to the worldwide shortage of Helium, many GC-MS users are now using hydrogen for carrier gas in their GC-MS analyses, however there are still fears about the safety of hydrogen and its reactivity with analytes. This study aims to show that hydrogen carrier gas produced by a hydrogen generator is suitable for GC-MS analyses and that use of hydrogen can give improved chromatographic results compared with helium as carrier gas.

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