Cookies

Like most websites The Analytical Scientist uses cookies. In order to deliver a personalized, responsive service and to improve the site, we remember and store information about how you use it. Learn more.

Fast Extraction of Metanephrine and Norm etanephrine

This application note describes a method of extraction for metanephrine and normetanephrine from synthetic urine using EVOLUTE EXPRESS CX 96 fixed well plates.

Introduction
Figure 1. Structure of metanephrine and normetanephrine
Figure 1. Structure of metanephrine and normetanephrine

The normalized metabolite concentrations of epinephrine and norepinephrine precursors have common utility in clinical diagnostics related to neuroendocrine tumors. Of particular interest are the selected metabolites metanephrine and normetanephrine. The challenges in population screening for these metabolites are time, cost and efficacy of sample preparation strategies required for trace level determinations (pg/mL-ng/mL levels) by liquid chromatography-tandem mass spectrometry.

Read the full article now

Log in or register to read this article in full and gain access to The Analytical Scientist’s entire content archive. It’s FREE and always will be!

Login if you already created an account

Or register now - it’s free and always will be!

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Analytical Scientist magazine
Register

Or Login as a Guest or via Social Media

Related Application Notes

Techniques & Tools Gas Chromatography

What is thermal desorption?

| Contributed by Markes

Generic Analyses of Different Monoclonal Antibodies with RP-(U)HPLC

| Contributed by YMC

Dubai Police uses TEA by Ellutia for explosives identification

| Contributed by Ellutia

Newsletter

Send me the latest from The Analytical Scientist.

Sign up now

Register to The Analytical Scientist

Register to access our FREE online portfolio, request the magazine in print and manage your preferences.

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Analytical Scientist magazine

Register