High-performance Mid-IR Liquid Analyzers for Bioprocess
contributed by DRS Daylight Solutions |
Bioreactor Monitoring: A New Application for the ChemDetect™ Liquid Analyzer
Executive Summary
The ChemDetect™ Analyzer is coupled to a novel micro flow cell that allows repeatable quanti-tative spectroscopic determination of liquid components. The system is calibrated to determine concentrations of relevant chemicals used in bioreactor feedstocks. Exercise of a test protocol for characterizing bioreactor feedstocks is carried out. It is found that the ChemDetect™ is sen-sitive to the relevant chemicals at better than 50 mg/L concentration over two decades of con-centration measurements for 90 second measurements. The analyzer can also differentiate be-tween mixtures of analytes, and was characterized to be stable to less than 4% drift over three days without calibration.
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