Like most websites The Analytical Scientist uses cookies. In order to deliver a personalized, responsive service and to improve the site, we remember and store information about how you use it. Learn more.


1. Introduction: TOFMS Resolving Power

The time-of-flight (TOF) mass analyzer was first proposed by W. E. Stephens in 1946[1]. With an unlimited mass range, an ability to show all of the masses in each spectrum, and a high spectral generation speed, the advantages of a TOF mass analyzer over the existing mass spectrometer design were immediately recognized. Within a few years, the first experimental mass spectrometers based on a TOF mass analyzer were built[2]. All varieties of time-of-flight mass spectrometers (TOFMS) have three major components: the Extraction Region, where ions are formed or where they are introduced and then extracted as a pulse of ions; the Drift Region, also called a Field-Free Region, where ions fly and separate in time according to their mass-to-charge ratio (m/z); and the ion detector (Figure 1).

Figure 1. Time-of-flight mass spectrometer concept.
Read the full article now

Log in or register to read this article in full and gain access to The Analytical Scientist’s entire content archive. It’s FREE!

Receive content, products, events as well as relevant industry updates from The Analytical Scientist and its sponsors.
Stay up to date with our other newsletters and sponsors information, tailored specifically to the fields you are interested in

When you click “Subscribe” we will email you a link, which you must click to verify the email address above and activate your subscription. If you do not receive this email, please contact us at [email protected].
If you wish to unsubscribe, you can update your preferences at any point.

Related Webinars
Fields & Applications Metabolomics & Lipidomics
Positional determination of the double bonds in fatty acyl chains of phospholipids using the EAD capabilities of the Zeno TOF 7600 system

| Sponsored by SCIEX

Techniques & Tools Spectroscopy
The Analytical Spectroscopy Technology Forum

| Sponsored by WITec GmbH, Bruker Optics, Hamamatsu Photonics Europe GmbH, and DRS Daylight Solutions

Techniques & Tools Liquid Chromatography
The Next-Level LC-MS Technology Forum

| Sponsored by ACD Labs, Agilent, Tosoh and Andrew Alliance (Waters)

Register to The Analytical Scientist

Register to access our FREE online portfolio, request the magazine in print and manage your preferences.

You will benefit from:
  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Analytical Scientist magazine