High resolution Saccharide and Polysaccharide Analysis using Small Particles

contributed by PSS | 12/15/2014

Application Note Food Analysis/Pharmaceutical Analysis

The PSS SUPREMA column with a reduced particle size of 5 μm offers a significant improvement in performance compared to traditional 10 μm materials and provides outstanding additional resolution, especially in the low molecular weight area, which is a major consideration when analyzing oligomeric polysaccharides.

Polysaccharides are very important in nature, occurring in food (starches in rice, wheat etc.) and plants (cellulose). Some polysaccharides are also produced commercially e.g. Dextrans, which are manufactured through the fermentation of sugar solutions. These are higher molar mass polysaccharides.

Dextrans are used in clinical and technical applications, where molecular weight is critical in determining the properties of the final product. Accurate determination of the molecular weight distribution is vital.

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