Highly sensitive targeted and non-targeted HPLC-MS analysis of PFAS

contributed by YMC | 02/27/2025

Per- and polyfluoroalkyl substances (PFAS) are persistent environmental pollutants known for their long lifetime and mobility. Their stability leads to accumulation in groundwater and soil, with proven harmful health effects. To mitigate environmental pollution, several PFAS compounds, such as perfluorooctanoic acid (PFOA), perfluorohexanesulfonic acid (PFHxS), and long-chain perfluoroalkyl carboxylic acids (C9-C14), are now regulated.

This technical note presents a method for identifying and quantifying PFAS using a YMC-Triart C18 HPLC column. This column, based on a robust hybrid silica particle, offers enhanced separation of isomers and improved analytical performance when coupled with mass spectrometry.

Log in or register to read this article in full and gain access to The Analytical Scientist’s entire content archive. It’s FREE!

Email*

Choose a password*

I have read and understand the Privacy Notice *

Stay up to date with our other newsletters and sponsors information, tailored specifically to the fields you are interested in

Receive communication from The Cannabis Scientist I want to stay up to date with the Mass Spectrometry field I want to stay up to date with the Spectroscopy field

When you click “Subscribe” we will email you a link, which you must click to verify the email address above and activate your subscription. If you do not receive this email, please contact us at [email protected].
If you wish to unsubscribe, you can update your preferences at any point.