Sample Preparation Method for Determination of Mycophenolic Acid in Plasma Using ISOLUTE ® SLE+
contributed by Biotage |
Introduction
Mycophenolic acid (Figure 1) is an active metabolite produced by the hydrolysis of the immunosuppressive agent Mycophenolate Mofetil in the body. It is considered important to control pharmacokinetic parameters such as AUC (area under the blood concentration-time curve) and trough concentration in order to prevent acute rejection after organ transplantation.
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