Fields & Applications Pharma & Biopharma, Liquid Chromatography, Polymers

Separation of statistic MMA-MAA Copolymers using Gradient SEC

contributed by PSS | 02/14/2017

Statistic copolymers of methyl methacrylate (MMA) and methacrylic acid (MAA) are used in pharmaceutical applications. The molar mass distribution, the chemical composition and the amount of comonomers are of importance. Characterization by gradient HPLC failed due to pronounced breakthrough peaks.
SEC-gradients has been successfully applied to measure the amount of MAA.

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