For faster, more precise, cost-effective separations, superior reproducibility and accurate results in analytical chromatography
In the world of analytical chemistry, chromatography has become the most widely used analytical technique due to the convenience, speed of separations, reproducibility, and quantitative accuracy of results that are inherent to the techniques. As instrument sensitivity continues to improve, suitable high purity solvents for the mobile phase and an effective sorbent stationary phase are becoming even more vital to success in the laboratory.
At Avantor™ Performance Materials, we manufacture innovative chromatography media products that support diverse separation techniques and applications, as well as high purity solvents to maximize separation performance and reliability in chromatography applications. Our highly efficient chromatography products are designed to deliver optimum performance, reproducibility and easy scale-up, without changing the quality of established method.
Sample Preparation
For as long as scientists have been analyzing compounds, there has been a need for sample preparation to extract and purify sample components. Today’s technology for sample preparation, Solid Phase Extraction (SPE), is grounded in the principles of chromatography and offers increased speed, reduced hazardous solvent use and exposure, and improved reproducibility of the separation when compared to other wet chemistry methods, such as liquid/ liquid extraction. Our scientists have been using and perfecting this method in our research and development labs since the 1970’s.
The purpose of sample preparation
Sample clean up — necessary to eliminate impurities and/or isolate the component of interest from the matrix. This helps to increase lifetime of the analytical column, prevents contamination of equipment, thereby protecting expensive instrumentation.
Sample concentration — in order to reach the detection limits of the analytical equipment. Sample preparation selectively concentrates the components of interest prior to analysis.
>> Download the full Application Note as PDF
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