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Fields & Applications Genomics & DNA Analysis

A Case of Identity

Successfully typing of bacteria at the species or strain level is not easy – fast, cost-effective methods like 16S ribosomal RNA gene sequencing lack accuracy, while technologies such as matrix-assisted laser desorption/ionization time-of-flight MS are more precise but remain expensive and laborious. Lukasz Krych and colleagues have developed an alternative: ON-rep-seq – an approach targeting specific fragments of the bacterial genome (1). “We’ve developed a system that assigns each bacterium a unique genetic barcode,” says Krych. “This allows us to run hundreds of samples simultaneously, drastically reducing the cost of analysis.” 

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About the Author

Jonathan James

Having thrown myself into various science communication activities whilst studying science at University, I soon came to realize where my passions truly lie; outside the laboratory, telling the stories of the remarkable men and women conducting groundbreaking research. Now, at Texere, I have the opportunity to do just that.

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