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Fields & Applications Sample Preparation, Technology, Data Analysis, Pharma & Biopharma, Clinical

Characterizing Opthalmic Viscosurgical Devices (OVDs) using a rotational rheometer

Characterizing Ophthalmic Viscosurgical Devices (OVDs) using a rotational rheometer

This application note discusses the methodology and results for the rheological characterization of Ophthalmic Viscosurgical Devices (OVDs) according to the International Standard ISO15798:2013.

Introduction

Ophthalmic Viscosurgical Devices (OVDs) are viscoelastic solutions or gels used to protect the corneal endothelium from mechanical trauma and to maintain intraocular space during eye surgery. They usually contain one or more of the following components; hyaluronic acid or its sodium salt, chondroitin sulfate or methylcellulose. As these materials are polymeric, they tend to be viscoelastic with their properties strongly dependent on factors such as concentration, molecular weight and molecular architecture as well as intra- or inter- molecular interactions in solution.

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