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Fields & Applications Spectroscopy, Petrochem

Extraction of Antiepileptic Drugs from Serum and Urine Using ISOLUTE® SLE+ Prior to LC-MS/MS Analysis

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Antiepileptic drugs (AED) are prescribed to suppress seizures in epilepsy patients. The ability to therapeutically monitor these drugs in patients is necessary for maintaining optimal medical care and managing any adverse effects of the drug. In this application note ISOLUTE SLE+ is demonstrated as an effective way to extract AEDs from serum and urine. The method was developed using a 96-well plate format to facilitate a high throughput workflow model

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