Fast Extraction of Metanephrine and Normetanephrine from Urine Using EVOLUTE® EXPRESS CX Prior to LC-MS-MS Analysis
sponsored by Biotage
A new solid phase extraction technology has been developed to speed up sample preparation by eliminating steps in the extraction workflow. This application note describes the extraction of metanephrine and normetanephrine from synthetic urine using this ‘load-wash-elute’ approach with EVOLUTE EXPRESS CX 96-well SPE plates. Recoveries exceeding 80% and excellent linearity over the range 10-70 ng/mL are achieved.