Making Sense of Metabolite Mixtures
Substructure analysis provides a means to decipher complex metabolic samples.
Justin J.J van der Hooft | | Opinion
Personalized medicine. Antibiotic discovery. Host–microbiome interactions. Plant breeding. What do these fields have in common? All have benefited from the realization that comprehensive small molecule profiles are essential to increase our knowledge of complex biological systems. Metabolites then represent key markers in such studies, and are often the end goal of analyses.
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