MS-based proteomics is providing clues about the huge range of responses patients exhibit
Matthew Hallam | | Quick Read
One of the major challenges we face in the fight against COVID-19 is a lack of knowledge surrounding host responses. Some are asymptomatic; others die – but what biological mechanisms underscore this chasmic disconnect?
Christoph Messner and colleagues are unraveling the mystery (1). Having spent the last few years developing an MS-based, high-throughput proteomics platform at the Francis Crick Institute, the team can quantify over 200 proteins per sample in less than 10 minutes. “It was obvious that our proteomics platform could be used as a powerful tool to study the plasma proteins of patients infected with SARS-CoV-2,” Messner says. “We set out to assess protein-level host responses with the hope of identifying markers for disease severity.”
Read the full article now
Log in or register to read this article in full and gain access to The Analytical Scientist’s entire content archive. It’s FREE and always will be!
Or register now - it’s free and always will be!
You will benefit from:
- Unlimited access to ALL articles
- News, interviews & opinions from leading industry experts
- Receive print (and PDF) copies of The Analytical Scientist magazine
Or Login via Social Media
By clicking on any of the above social media links, you are agreeing to our Privacy Notice.