Two-photon laser microscopy reveals unique tumor tissue features that may improve oncological surgery
Jonathan James | | Quick Read
Imaging technologies are invaluable in the operating theater. Modern approaches allow surgeons to visualize cancerous tissue in real time; a reassuring addition for those holding the scalpel. There is, however, room for improvement; low spatial resolution means that smaller metastatic lesions may go unnoticed.
Thomas Schnelldorfer and colleagues have developed a new protocol capable of classifying tissue biopsies with an accuracy of 97.5 percent by combining two-photon laser scanning microscopy with advanced imaging and statistical software (1). “We’ve demonstrated that we can identify specific cellular and tissue-level features at the microscopic level – distances as small as 1/100,000 the width of a human hair,” says Schnelldorfer.
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