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The Analytical Scientist / Issues / 2025 / June / What’s Happening at HPLC on Wednesday?
Chromatography News and Research

What’s Happening at HPLC on Wednesday?

Real-world challenges, 3D-printed solutions, and new thinking in non-target screening

06/18/2025 4 min read

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0625-107-Key-Event-HPLC_Teaser-Day-3.png

Credit: Adobe Stock (Edited)

Today kicks off with the first-ever Industry Stories session – a fresh initiative designed to spotlight real-world problem solving, complete with missteps, lessons learned, and a healthy dose of honesty. With speakers from pharma giants like Eli Lilly, Sanofi, and AstraZeneca – expect insight you won’t find in a journal article.

Later, we zoom in on the world of miniaturization with Adam Woolley, one of our “Three Gurus of Miniaturized Chemical Analysis,” and close the day with Thomas Letzel on non-target screening – picking up where our May webinar left off.

Today’s Must See

08:30-10:15 (The View, Level 4) – Industry Stories 1 (Chaired by Amanda Guiraldelli and Stefan Lamotte)

“Industry stories” are a new initiative to help active chemical analysts expand their chromatographic knowledge, discover new automation and data processing methods, and, above all, learn from each other's experiences. These sessions will showcase “the most interesting examples of problem solving in industry,” according to Gert Desmet. “In addition to typical success reports, here we’ll encourage presenters to reveal the mistakes they’ve made (if any), and any challenges or setbacks faced.”

The first batch of presentations features speakers from several leading pharma companies: Eli Lilly, Novartis, Sanofi, Johnson & Johnson, and AstraZeneca.

14:40 (Foyer, Level 3) – 3D Printed Microfluidic Chromatography Systems (Adam Woolley)

Adam Woolley was one of our Three Gurus of Miniaturized Chemical Analysis – a feature from last year that tackled miniaturized separation technology, the rise of 3D-printing capabilities, and recent advances in microfluidics. Here’s what Woolley said about the current state of miniaturized separation technology:

“Given the maturity of the miniaturized chemical analysis field, one might assume that innovative work is no longer occurring. On the contrary, novel advances continue in miniaturized analysis, particularly for droplet microfluidics in cell analysis, omics, 3D printing as a tool to create miniaturized systems, and a variety of electrochemical sensing platforms. Many of the drivers of miniaturization remain unchanged from the early days: automation, scalable/low-cost/disposable devices, and reduced chemical consumption. Furthermore, the ability to achieve novel assay designs and outcomes through microfabrication continues to motivate analytical scientists.

“But the two key questions remaining to be addressed with miniaturization are: i) how can analytical scientists continue to innovate in a maturing field? and ii) how can multiple ‘breakthrough applications’ be brought to fruition?”

James Grinias, who was also featured in that feature, is giving a talk on Analyzing Complex Samples with Compact Capillary LC at 16:30 (Foyer, Level 3).

17:15 (The View, Level 4) – Modern Chromatography for Non-Target Screening and (statistical) Data Handling Concepts (Thomas Letzel)

If you joined our Breaking Down Barriers with Non-Target Screening webinar back in May (if not, you can check out the on-demand version here), you’ll remember Thomas Letzel’s clear and compelling introduction to the analytical process in NTS. Today, he’s back to expand on that theme, covering how modern chromatography can support robust non-target workflows, and what statistical concepts are essential for making sense of the data flood.

Whether you're deep in the NTS world or just NTS-curious, this is one not to miss.

Tomorrow’s Planner

08:30-09:15 (Auditorium B): Tutorial: No molecule is above the law (no matter how big and strong they are) (Peter Schoenmakers)

08:30-10:15 (The View, Level 4): Session: EUChem Sample Preparation (Chared by Elia Psillakis and Marcella Segundo)

11:10-11:30 (Foyer, Level 3): Comprehensive 2D LC-MS to study phenolic evolution in single vineyard wines (André de Villiers)

Thought of the Day

“I continue to be excited about the prospects of 3D printing in separation science, especially in the area of sample preparation. People are combining novel geometric designs with advances in material science to come up with more effective analyte extraction devices that can be manufactured by anyone with a low-cost printer. This area is sure to continue emerging in coming years.” – James Grinias

Aprés-Sci

Wander off the main squares and you might stumble into Minnewaterpark, where swans glide and locals picnic. It’s peaceful, green, and just a short walk from the conference venue. Bring a cone of frites and call it dinner.

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