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Techniques & Tools Mass Spectrometry, Spectroscopy

An Elemental Regeneration

Prior to moving to Switzerland, I did my PhD at Indiana University in Gary Hieftje’s group, where I studied a new form of velocity-based mass spectrometry – distance-of-flight mass spectrometry (DOFMS). My research into DOFMS was formative, and taught me about mass spectrometer design, construction, and operation. I’ve carried the interest and expertise I gained in velocity-based mass spectrometry to my current work at ETH Zurich, developing analytical methods for the high-throughput analysis of diverse inorganic nanoparticles from environmental samples by ICP-TOFMS.

As I began searching for a postdoc position, I was aware of renewed interest in full-spectrum atomic mass spectrometry, largely because of key applications in biomolecule detection and laser-ablation imaging. The potential encouraged me to join the Günther group, who were central to the revival of inductively coupled plasma time-of-flight mass spectrometry (ICP-TOFMS).

ICP-TOFMS rediscovered

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About the Author

Alexander Gundlach-Graham

Alexander Gundlach-Graham earned his Ph.D. in 2013 in the group of Gary Hieftje at Indiana University for the development and characterization of distance-of-flight mass spectrometry (DOFMS). Afterwards, he received a Marie-Curie Fellowship to complete postdoctoral research in the lab of Detlef Günther at ETH Zurich. Alex currently holds an Ambizione fellowship through the Swiss National Science Foundation. His research focuses on ICP-time-of-flight mass spectrometry and its application for high-resolution laser-ablation ICP-MS imaging and nanoparticle detection and sizing.

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