Gurus of 2DMS
Advances in our ability to crunch data continue to lay the foundations for the rise of multidimensional MS in mainstream analytics. But what exactly is 2DMS – and how can the technique transform the field?
Matthew Hallam | | Longer Read
Two-dimensional techniques are shifting the landscape of analytical science – ramping up levels of data acquisition and offering unparalleled insights into the phenomena we investigate. Our thirst for “more” – especially when analyzing highly complex samples – has driven us out of the first dimension in multiple techniques; 2D NMR spectroscopy has been around for decades, and various flavors of multidimensional chromatography have proven utility in a range of applications. But now, it’s time for the spotlight to shift. Prepare to enter a new dimension – of MS.
“I’m a Fourier-transform ion cyclotron resonance (FT-ICR) mass spectrometrist, and Associate professor at Boston University School of Medicine and Professor of Chemistry at the University of Warwick. Our work has focused on bringing 2DMS to the analytical mainstream, with the hope of developing routine applications in chemistry and biology.”
“I was lucky enough to conduct research under Arlen Kauffman during my undergraduate studies. Arlen introduced me to Graham’s work on ambient ionization and molecular imaging, and I eventually became an “Astonite” myself, developing novel ion trap methods for miniature and portable mass spectrometers.”
Maria van Agthoven
“I’ve worked on several 2DMS projects in labs from Florida State University to the Université de Lille Sciences et Technologies and the University of Warwick. Now, I’m based at the University of Innsbruck, Austria, where I’m continuing this work. The hope? That 2DMS will one day become as commonplace as other analytical techniques.”
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