The Trouble with Metabolomics
The pursuit of the metabolome may no longer be a novel field, but it remains the biggest analytical challenge.
Georgios Theodoridis |
Within the area of systems biology, analytical scientists are most familiar with metabolomics because it uses well-known techniques (such as NMR spectroscopy, LC-MS, GC-MS) and because it is often swift to embrace new advances, such as high-resolution mass spectrometry (MS). But with multiple advanced tools comes much data. Indeed, a wealth of data points lay hidden in a given ion chromatogram, but some of these will be useless signals, so we need statistics to help us. And that’s where the tricky part begins.
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