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Techniques & Tools Spectroscopy, Clinical, Translational Science

This Week’s Spectroscopy News

Essential Reading

Michelin Star Spectroscopy

Researchers from Yonsei University, Republic of Korea, have developed a switchable flavor compound (SFC) loaded on a hydrogel matrix, creating a new type of enhanced cultured meat. The team employed a variety of spectroscopic techniques, including Raman, NMR and UV-Vis, to design and assess SFC’s chemical structure, thermal responsivity, as well as flavor stability. This led the team to introduce two sulfur compounds – 2-methyl-3-furanthiol and 3-mercapto-2-pentanone – known to contribute to the savory and umami flavors of cooked beef. Ultimately, the researchers were then able to achieve a flavor profile almost identical to that of traditional beef. Read the full writeup!

Direct Detection of Molecular Chirality

A new nuclear magnetic resonance (NMR) technique allows for the direct detection of molecular chirality, eliminating the need for additional chiral agents. The study presents a method that uses both electric and magnetic dipoles to differentiate between enantiomers. This innovation could streamline applications in drug development and materials science where chirality plays a critical role. Read the full writeup!

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Also in the news…

NMR-based molecular-level characterization allows researchers to understand how siRNA is distributed within its lipid nanoparticle (LNP) core – crucial for optimizing LNP formulations. Link

Portable spectroscopy system that consists of a laser diode and a CMOS-based camera can be placed on the head to non-invasively monitor changes in brain blood flow and volume to assess stroke risk. Link

Depixus launches MAGNA One, a magnetic force spectroscopy instrument, which the company says is “the world’s first consumer laboratory instrument for exploring individual biomolecular interactions at scale.” Link 

Research reveals the forensic importance of decay-induced spectral alterations in ante-mortem and post-mortem injuries using ATR-FTIR. Link

Researchers use Raman spectroscopy combined with machine learning and chemometrics to identify atherosclerotic carotid stenosis from serum. Link

In a similar vein… Researchers combine Raman spectroscopy and machine learning for the identification of breast cancer. Link

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About the Author
James Strachan

Over the course of my Biomedical Sciences degree it dawned on me that my goal of becoming a scientist didn’t quite mesh with my lack of affinity for lab work. Thinking on my decision to pursue biology rather than English at age 15 – despite an aptitude for the latter – I realized that science writing was a way to combine what I loved with what I was good at.

From there I set out to gather as much freelancing experience as I could, spending 2 years developing scientific content for International Innovation, before completing an MSc in Science Communication. After gaining invaluable experience in supporting the communications efforts of CERN and IN-PART, I joined Texere – where I am focused on producing consistently engaging, cutting-edge and innovative content for our specialist audiences around the world.

 

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