A Screening Method for Major Metabolites of JWH-018 and JWH-073 in Human Urine

contributed by SCIEX | 07/10/2014

This application note describes a novel screening method for major metabolites of two main active ingredients of K2: JWH-018 and JWH-073. This method takes advantage of the QTRAP^® system to perform an information dependent acquisition (IDA), using multiple reaction monitoring (MRM) as a survey scan, and automatically triggering enhanced product ion (EPI) scans, or linear ion trap full-scan MS/MS. EPI spectra are submitted for searching against an MS/MS spectral library for confirmation.

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