Fast GCMS/MS analysis of pesticides

Summary

This case describes the determination of pesticide residues in food using the well-established QuEChERS method (Quick Easy Cheap Effective Rugged Safe). The measurement was obtained using single quadrupole GCMS in selected ion monitoring (SIM) or SCAN modes, GCMS/MS using multi-reaction mechanisms (MRM) and LCMS/MS (MRM). Applying single quadrupole GCMS full scan modes provides maximum safety in avoiding false positive or false negative identification, as matrix signals can interfere with the signals of the target compounds. Here, large volume injections are needed to obtain the sensitivity required [1].