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October 2024 Issue of The Analytical Scientist

The September/October issue’s cover feature examines how the success of COVID-19 vaccines has fueled a nucleotide-based therapy “big bang” – and what challenges lie ahead for analytical scientists in characterizing these complex molecules. In "Upfront," we spotlight a breakthrough in cancer diagnostics – a new electrokinetic sensor capable of diagnosing glioblastoma in under an hour using just 100 microliters of blood. Meanwhile, in "In My View," Isabelle Kohler shares personal insights on the realities of PhD life, offering tips on building resilience and support networks; and we also celebrate the 20th anniversary of electromembrane extraction (EME), with Stig Pedersen-Bjergaard reflecting on the technique’s evolution and its potential to transform green sample preparation. In our Core Topics, Joseph Loo explains why native mass spectrometry is now essential in biochemistry labs, especially for studying large protein complexes and viral assemblies. And finally, In "Sitting Down With..." we chat with Gary Patti, who reflects on how working across disciplines brings fresh perspectives to science, offering exciting new avenues for discovery.

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Articles featured in this issue

Techniques & Tools Sensors

Electrokinetic Sensor Rapidly Diagnoses Brain Cancer

| James Strachan | 5 min read

Biochip diagnoses glioblastoma in under an hour using electrokinetic technology to detect EGFR biomarkers

Fields & Applications Genomics & DNA Analysis

Ancient Bubblegum

| Markella Loi

Our Mesolithic ancestors could have suffered from periodontitis due to frequent chewing of “gum” (red fox fur), suggests metagenomic analysis

Techniques & Tools Microscopy

Real-Time Window into the Brain

| James Strachan

New high-speed microscopy technique developed by UC Davis researchers enhances real-time neural activity monitoring

Business & Education Professional Development

Work Hard, Network Harder

| Isabelle Kohler | 5 min read

Tips and tricks for a happy (and healthy) PhD journey

Techniques & Tools Sample Preparation

Impactful Sample Prep Series: EME Turns 20

| Stig Pedersen-Bjergaard | 5 min read

Recently commercialized, amenable to operation in multi-well plates, and fundamentally green – has EME reached an inflection point?

Fields & Applications Forensics

The Future of Forensics

| Roxanne Zascavage | 4 min read

With additional forensic-specific analysis software, nanopore sequencing platforms are set to revolutionize the industry

Fields & Applications Polymers

Navigating Medtech Polymer Analysis – Together

| Sponsored by Tosoh | 6 min read

Experts from TOSOH and the Galien Paris-Saclay Institute collaborate to overcome increasingly complex characterization challenges in biopolymer analys

Techniques & Tools Mass Spectrometry

Going Native

| Joseph Loo | 8 min read

Native MS has become essential in biochemistry labs. So what is preventing more researchers from “going native?”

Fields & Applications Pharma & Biopharma

Pushing the Boundaries of Bioprocessing

| Jungmin Oh | 4 min read

Biopharma tech continues to advance so why is downstream processing such a headache?

Techniques & Tools Spectroscopy

Through the Spectroscopic Glass

| Richard Crocombe | 5 min read

What does the future hold for optical spectroscopy and diagnostics?

Other issues of 2024