Measuring Protein Aggregation with the Viscotek SEC-MALS 20
contributed by Malvern Panalytical |
Introduction
Protein aggregation is recognised as a major issue in the biopharmaceutical industry. Proteins have a tendency to aggregate over time and the risk for biologic drugs is that the presence of aggregates will stimulate an immune response. Size-exclusion chromatography (SEC) is a powerful tool that is commonly used to look at the aggregation of proteins.
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