App Notes

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With the introduction of TSKgel UP-SW3000 silica-based UHPLC columns increased speed and higher resolution can be achieved for the separation of antibody fragments, monomers, and dimers. These size exclusion columns feature the same pore size as the renowned TSKgel G3000SWXL.

This poster is a summary of various sample preparation strategies for the extraction of MMA from serum without the necessity for derivatization, prior to LC-MS/MS analysis. Also, the simplicity of transfer to an automated sample preparation platform is evaluated.

Presented here is a rapid and reliable sample preparation method using Support Liquid Extraction (SLE) to extract a suite of 30 urinary steroid hormone metabolites. Matrix effects are eliminated by the ISOLUTE^® SLE+ protocol giving a sensitive, linear assay with excellent clinical utility.

A straightforward, cost-effective and quick method, coupling SPE methodology with LC/MS/MS for the sensitive detection of four aflatoxin compounds in the hops complex matrix with recoveries of 97-119% at 6-25 ppb levels.

nanoDSF is a new and powerful tool for rapid screening approaches in biosimilar development. It enables narrowing down the number of promising candidates in hours instead of days or weeks. Download the full application note to learn more.

Cannabis (marijuana) has been legalized for recreational and/or medical use by 23 states, the District of Columbia, and the territory of Guam.

In this Application Note, we use thermal desorption (TD) for collection and analysis of whole cigarette emissions, and couple it with flow-modulated GC×GC–TOF MS, to enable smoke constituents to be routinely and confidently sampled, separated and identified.

EU Regulation 1169/2011 defines rules for nutrition declaration on foodstuffs. The objective is to provide food information to the general public and to label food ingredients that are hazardous to health when consumed in larger quantities. This Application Note describes the determination of four sugars in honey.

TLC is a simple and convenient tool for monitoring classical organic syntheses. Standardized HPTLC may additionally provide reliable analytical endpoints and significantly improved separation.