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App Notes

Results 971–980 of 1444

Analysis of Synthetic Opiates and Novel Analgesics in Urine using SPE and HPLC-MS/MS

| Contributed by UCT

Opiate abuse is drastically on the rise in the United States. In addition to traditional naturally occurring opiates, forensic toxicologists also need the ability to rapidly identify synthetic opioid-like drugs.

Pesticide Detection using SERS Techniques

| Contributed by Ocean Optics

In this application note, we evaluate the effectiveness of surface enhanced Raman spectroscopy (SERS) to measure trace levels of imidacloprid, one of a class of insecticides linked to honeybee loss.

Determination of mycotoxins with photochemical post column derivatization

| Contributed by Knauer

Using a photochemical reactor for post column derivatization in combination with the AZURA Analytical HPLC system and Eurospher II C18 column, it was possible to detect ZON, DON and the four aflatoxins B1, B2, G1 and G2 in one chromatographic run.

Fast and reproducible method for cell disruption

| Contributed by Retsch

Bead beating is a very effective and reliable method greatly superior to the manual procedure involving a Vortexer. RETSCH's Mixer Mill MM 400 can be equipped with tube adapters for high throughput, ensuring a reproducible, fast and efficient cell disruption process with very good results.

Analysis of Paracetamol in different formulations with TLC – MS

No sample preparation. No doubts. No headaches. The analysis of Paracetamol is performed using an elution based “TLC – MS interface” coupled with an “expression CMS”. Because of the high matrix tolerance of TLC, very easy sample preparation methods can be applied for suppositories, pain syrup and pills

Analysis of Monoclonal Antibody and Protein Aggregates Induced by Denaturation using a Novel SEC Column

| Contributed by Tosoh

This application note will show the superior resolving power of the TSKgel UltraSW Aggregate column for the analysis of monoclonal antibody and metalloprotein aggregates formed under forced denatured conditions.

Fast Analysis of IgG Charge Heterogeneity by Ion Exchange Chromatography

| Contributed by Tosoh

Evaluation of strong and weak cation exchange columns and dependence of separation on mobile phase PH.

UHPLC Glycosylation Analysis with TSKgel Amide-80 2 μm HILIC Columns

| Contributed by Tosoh

Glycosylation is one of the most common forms of post-translational modification of proteins.

DAR Analysis of Antibody-Drug Conjugate by Hydrophobic Interaction Chromatography

| Contributed by Tosoh

In this application note an ADC was analyzed using a TSKgel Butyl-NPR column.

Rapid and Accurate Therapeutic mAb Aggregate Analysis Using TSKgel® UP-SW3000, 2 μm, SEC Column

| Contributed by Tosoh

This application describes the use of a 4.6 mm ID × 15 cm TSKgel UP-SW3000 SEC column for fast and accurate mAb aggregate analysis without compromising the quality of the aggregate determination or reproducibility.

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