Pellicular Anion-Exchange Oligonucleotide Chromatography Coupled with High-Resolution Accurate Mass (HRAM) Mass Spectrometry

contributed by Thermo Fisher Scientific | 09/26/2013

To couple high-resolution pellicular anion-exchange liquid chromatography (pAXLC) of oligonucleotides with HRAM mass spectrometry (MS) and automated desalting to identify impurities and isomeric variants in synthetic oligonucleotides

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