A Golden Ratio for Gut Disorders
Could the permeability ratio be used to diagnose and monitor gut disorders less invasively than traditional colonoscopy?
Luke Turner |
Inflammatory bowel disease (IBD) is on the rise across the globe – especially in industrialized countries. By 2015, an estimated three million people in the US had received a diagnosis of either Crohn’s disease or ulcerative colitis, the two conditions collectively known as IBD (1). Characterized by chronic inflammation of the gastrointestinal tract, symptoms of the disease include stomach pain and swelling, bloody diarrhea, and weight loss. Typically, IBD is diagnosed and monitored through colonoscopy, which assesses structural damage to the intestine’s gut-blood barrier. But colonoscopy is invasive and requires anesthesia – and Marcin Ufnal of the Medical University of Warsaw might have found a better alternative.
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