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Fields & Applications Mass Spectrometry, Technology, Metabolomics & Lipidomics

The Super-Resolution Revolution

I grew up wanting to be a surgeon, a laudable ambition with one fatal flaw – I am extremely squeamish. Luckily, I loved physics just as much as biology. Completing my PhD here at the UK’s National Physical Laboratory (NPL) taught me just how important measurement science is – and sparked my fascination with mass spectrometry imaging (MSI). Over the next 20 years, I developed a world class capability in secondary ion mass spectrometry (SIMS). Most of our work was in devices, organic semiconductors, and advanced manufacturing, but I could see huge potential for these techniques in biology.

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About the Author

Ian Gilmore

Ian Gilmore is a Senior NPL Fellow and Head of Science at NPL. He is the founder of the National Centre of Excellence in Mass Spectrometry Imaging (NiCE-MSI) at NPL, where he conceived of the 3D OrbiSIMS instrument and led the project to build it. The Gilmore group will lead the high-resolution 2D and 3D SIMS imaging for the Grand Challenge.

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