The Super-Resolution Revolution
A unique feature of the Grand Challenge is the inclusion of a brand new technique – 3D OrbiSIMS. In an interview with Charlotte Barker, Ian Gilmore explains why he decided to combine SIMS with an Orbitrap, and how his dream of super-resolution metabolic imaging is helping to map cancer.
Ian Gilmore |
I grew up wanting to be a surgeon, a laudable ambition with one fatal flaw – I am extremely squeamish. Luckily, I loved physics just as much as biology. Completing my PhD here at the UK’s National Physical Laboratory (NPL) taught me just how important measurement science is – and sparked my fascination with mass spectrometry imaging (MSI). Over the next 20 years, I developed a world class capability in secondary ion mass spectrometry (SIMS). Most of our work was in devices, organic semiconductors, and advanced manufacturing, but I could see huge potential for these techniques in biology.
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