Fields & Applications Pharma & Biopharma

UHP-SEC Analysis of Immunoglobulins with TSKgel UP-SW3000

Antibody therapeutics are dominating the biopharmaceutical market. In 2013, six of the top ten global drug brands were monoclonal antibodies (mAbs). The characterization of these complex biomolecules is a major challenge in process monitoring and quality control. The main product characteristics to be monitored by chromatography are aggregate and fragment content, glycosylation pattern and charged isoforms.

09/16/2015

sponsored by Tosoh

The standard QC method for mAb aggregate and fragment analysis is size exclusion chromatography (SEC). A new series of 2 micron silica based UHPLC columns with 25 nm pore size can be applied to either increase speed or improve resolution of the separation of antibody fragments, monomers, and dimers.

Email*

Choose a password*

I have read and understand the Privacy Notice *

Stay up to date with our other newsletters and sponsors information, tailored specifically to the fields you are interested in

Receive communication from The Cannabis Scientist I want to stay up to date with the Mass Spectrometry field I want to stay up to date with the Spectroscopy field

When you click “Subscribe” we will email you a link, which you must click to verify the email address above and activate your subscription. If you do not receive this email, please contact us at [email protected].
If you wish to unsubscribe, you can update your preferences at any point.