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The Analytical Scientist / Issues / 2024 / Sep / This week’s Mass Spec News (2)
Mass Spectrometry

This week’s Mass Spec News

Reflecting on Dorrestien’s MS journey; uncovering the toxicity of the Great Salt Lake, introducing iTPAUMS and more…

09/20/2024 2 min read

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Credit: Adobe Stock

Essential Reading

Great Salt Lake, Greater Toxicity

As the Great Salt Lake (Utah, USA) continues to shrink, exposing more of its lakebed, concerns are growing about the potential health impacts of dust from this increasingly barren landscape. 

Researchers from the University of Utah have recently conducted a study focusing on the chemical composition of dust particles originating from the exposed lakebed. To investigate the composition of these dust particles, the research team used inductively coupled plasma mass spectrometry (ICP-MS).

The results indicate that the dust from the Great Salt Lake contains elevated concentrations of several metals, including arsenic, lithium, copper, manganese, iron, and lead. Notably, the levels of arsenic and lithium exceeded the US Environmental Protection Agency’s residential regional screening levels, indicating a potential health risk for populations living downwind of the lake.

Read more here!

Worth Your Time...

Researchers from Zhejiang University introduce iTPAUMS: an approach combining thermal proteome profiling with affinity ultrafiltration mass spectrometry to analyze natural products. Link 

Matthias Mann and his colleagues employ deep visual proteomics (DVP) to analyze colorectal adenomas – identifying protein markers and metabolic shifts linked to recurrence that could improve personalized management strategies. Link

Workflow combining LC-HRMS and chemiluminescence – designed for N-nitrosamines monitoring in wastewater treatment – improves assessment of their prevalence and persistence, and identifies previously uncharacterized species. Link  

Triacylglycerol profiling offers a faster, complementary screening for authenticating hazelnut cultivar and origin, according to a study using GC-MS and chemometrics. Link 

Community Corner
#ArchiveDive

This week we reflect back on Pieter Dorrestein's journey to make mass spec more impactful through innovation and open science. 

“One day, MS will be incorporated into smartphones, allowing consumers to conduct analysis in real-time. When will that happen? It will depend on whether the community makes an effort to organize itself; if it does not, I fear that progress will continue at a snail’s pace,” he said in the interview. 

What do you think are the biggest challenges or opportunities in making this vision a reality? Has the community managed to make any progress?

Let us know what you think!

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