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Techniques & Tools Liquid Chromatography, Proteomics, Microscopy

Slip Flow Star

The -omics era has inspired creativity across analytical chemistry by posing interesting new challenges. In my case, the stimulus to think about new materials for separations came at the 1999 Gordon Conference on Analytical Chemistry, which included the emerging field of proteomics. I was taken aback by the images of stained two-dimensional gels, which are riddled with streaks, especially for large proteins, and wondered why no-one commented on these and how they must hide lower abundance proteins. When I asked, people said “that’s just the way it is”. The gel images made me think about what kind of material could enable protein electrophoresis without streaks.

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About the Author

Mary Wirth

W. Brooks Fortune Distinguished Professor, Department of Chemistry, Purdue University

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