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Techniques & Tools Liquid Chromatography, Proteomics, Microscopy

Slip Flow Star

The -omics era has inspired creativity across analytical chemistry by posing interesting new challenges. In my case, the stimulus to think about new materials for separations came at the 1999 Gordon Conference on Analytical Chemistry, which included the emerging field of proteomics. I was taken aback by the images of stained two-dimensional gels, which are riddled with streaks, especially for large proteins, and wondered why no-one commented on these and how they must hide lower abundance proteins. When I asked, people said “that’s just the way it is”. The gel images made me think about what kind of material could enable protein electrophoresis without streaks.

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About the Author

Picture of Author Mary Wirth

Mary Wirth

<span lang="EN-US">Mary Wirth is the W. Brooks Fortune Distinguished Professor in the Department of Chemistry at Purdue University.&nbsp; </span>She researches new materials for protein separations, including characterizing heterogeneity of protein drugs, improving top-down proteomics, and discovering trace protein biomarkers for screening of early aggressive cancer.&nbsp; Mary received her BS degree in 1974 from Northern Illinois University and her PhD in 1978 from Purdue University.&nbsp; She is a Fellow of the Society of Applied Spectroscopy, and a Fellow of the American Association for the Advancement of Science. Her research has been recognized by awards that include the ACS Analytical Division Award in Spectrochemical Analysis, the EAS Gold Medal Award in spectroscopy, the ANACHEM Award, the Eastern Analytical Symposium Award for Outstanding Achievements in the Fields of Analytical Chemistry, the Dal Nogare Award from the Chromatography Forum of the Delaware Valley, and the Jubilee Medal from the Chromatography Society.&nbsp;

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