Techniques & Tools Sample Preparation, Forensics, Clinical

A Modified QuEChERS Approach for the Extraction of DOA’s from Post-mortem Liver

contributed by UCT | 04/03/2017

Blood and urine are by far the primary biological fluids of choice for toxicology analysts to work with in the lab, however, other matrices are often tested to either substantiate the concentrations found in blood and urine or in instances of limited sample. Liver is the primary alternative tissue used for toxicological analysis based on the biological role it plays in the metabolism of drugs and toxicants in the body. Drugs become concentrated in this vital organ and can be found even when there are no detectable quantities present in the blood. This additional information becomes very critical when trying to determine the cause of death.

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