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Sigma Aldrich

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LC/MS/MS Analysis of Aflatoxins in Hops After Solid Phase Extraction Cleanup

| Contributed by Sigma Aldrich

A straightforward, cost-effective and quick method, coupling SPE methodology with LC/MS/MS for the sensitive detection of four aflatoxin compounds in the hops complex matrix with recoveries of 97-119% at 6-25 ppb levels.

Analysis of Pesticide Residues in Cannabis Using QuEChERS Extraction and Cleanup Followed by GC/MS/MS Analysis

| Contributed by Sigma Aldrich

Cannabis (marijuana) has been legalized for recreational and/or medical use by 23 states, the District of Columbia, and the territory of Guam.

Analysis of Polychlorinated Biphenyls in Fish Oil Using Supelclean EZ-POP NP, Silica Gel SPE, and an SLB-5ms GC Column

| Contributed by Sigma Aldrich

This method uses solid phase extraction with Supelclean EZ-POP NP and a small silica gel cartridge for additional cleanup. The resulting extract has low background and a full range of PCB congeners can be analyzed by GC/ECD.

High Resolution and High Efficiency Separations of mAbs and ADCs Using Proteomix HIC Columns

| Contributed by Sigma Aldrich

Hydrophobic interaction chromatography (HIC), a technique commonly used for protein separation, is also used as an orthogonal method to size-exclusion and ion-exchange chromatography for the characterization of monoclonal antibodies and antibody-drug conjugates.

NEW! 200 m GC Columns for Detailed Analysis of cis/trans FAME Isomers

| Contributed by Sigma Aldrich

Over the last half of the previous century, the use of partially hydrogenated vegetable oil (PHVO) replaced the use of animal fats for baking purposes in most western countries.

Analysis of Vitamin D in Milk and Infant Formula using UHPLC-MS-MS per AOAC Method 2011 11

| Contributed by Sigma Aldrich

Fortification of milk, dairy products, infant and adult nutritionals with vitamin D is required in many countries to provide additional dietary vitamin D.

Extraction of Permethrin Pesticides from Spinach Using QuEChERS Methodology with Automated Shaking

| Contributed by Sigma Aldrich

The results obtained using an automated shaker for extraction were compared to a standard QuEChERS protocol involving manual shaking of the spinach extracts for 1 minute.

Aminoglycoside Analysis in Honey Using Molecularly Imprinted Polymer Cleanup and LC/MS/MS Detection

| Contributed by Sigma Aldrich

Extraction and analysis of six aminoglycosides from honey using molecularly imprinted polymer (MIP) solid phase extraction (SPE) to successfully quantitate six aminoglycosides by LC/MS/MS at 50 ng/g.

Quantifying Picogram Concentrations of Aflatoxin M1 in Liquid Milk

| Contributed by Sigma Aldrich

A fast method for the cleanup, analysis, and quantification of aflatoxin M1 in milk samples to EU regulatory standards (0.025 μg/kg) was developed using Supel Tox AflaZea SPE and LC/MS analysis.

A Fast and Robust HPLC Separation of Bile Acids and Their Conjugates with Ascentis Express C18

| Contributed by Sigma Aldrich

Helping to Elucidate the Role of Plasma Bile Acid Signalling in Humans

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