Supelco

Using a Simple Procedure for Simultaneous Cleanup of Phospholipids and Proteins

The monitoring of drugs of abuse in biological matrices requires methodology sensitive enough to monitor well below therapeutic levels and selective enough for clear identification of specific drugs without false positives.

In this study, optimized methods are presented for sample preparation and chiral chromatography for the LC/MS analysis of amphetamine and methamphetamine enantiomers in urine.

Analysis of polyaromatic hydrocarbon compounds (PAHs) in butter can pose a special challenge due to its high fat content and the lipophilic nature of PAHs; recovery often results in co-extraction of the fatty matrix.

Unlike low-tech carbon black and activated carbon, specialty carbon adsorbents are engineered materials, manufactured from highly pure synthetic polymers.

A 3D PCA plot visually showed that ionic liquid columns fill an empty area of the available selectivity space, which should clearly enhance the separation capacity of the GC technique.

In this study, re-equilibration times in HILIC, for both aqueous:organic gradients and buffer gradients are systematically explored. Repeatability of retention and selectivity is examined as a function of equilibration time.

Current extraction and cleanup techniques for fatty samples are time-consuming, expensive, and provide insufficient background removal prior to analysis. For this reason, a new approach was developed.

Differentiation of Illicit D-Methamphetamine from Over-the-Counter L-Methamphetamine by LC-MS

Using Supel QuE Z-Sep QuEChERS Sorbents and SPB-608 Capillary GC Columns