September 2014 Issue of The Analytical Scientist

We started The Analytical Scientist with a bold, three-word mission: recording, scrutinizing, celebrating.

The spine-tingling story behind megavolt electrostatic ionization mass spectrometry

Miniature chips aim to deliver portable – or massively parallel – nuclear magnetic resonance (NMR) spectroscopy

The Analytical Scientist Innovation Awards (TASIAs) return for 2014 to showcase new technologies, instruments and software solutions that are out of this world

IACE-MALDI-MS takes allergy testing to the next level by identifying the milk proteins that cause the reaction

An Imperial College London professor has been awarded the Royal Medal for his work in biomolecular mass spectrometry

Having attended Pat Sandra’s lecture at Riva 2014 and read The Analytical Scientist’s feature on sample preparation, I can certainly say that Pat has succeeded in igniting discussion on the topic. Here’s my silver Sickle’s worth.

Conventional bulk ion-selective sensors have been extensively studied and are well understood. Now, they must be miniaturized for cutting-edge applications, allowing us to blur the line between sensing and bulk solution chemistry.

It is clear that analytical science is interdisciplinary, but what exists at its heart –and how do we instill that in students?

More than a year has passed since I expressed my hopes for chemometrics to take center stage in this magazine. Where are we now?

The chemical analysis chain is only strong if the quality system takes into account each and every link – including those that can sometimes be neglected or forgotten.

Many of the world’s leading experts came together for the 10th European Pesticide Residue Workshop (EPRW) in Dublin, Ireland, this summer for an international exchange of information and experience.

Swamped by information and demands for increased productivity, it can be difficult to organize our time – and minds – to facilitate “Eureka!” moments.

Think you’ve got what it takes to be an expert witness? Certainly, scientific expertise is of great importance – but there’s a lot of work ahead.

Sitting Down With… Ulrich Panne, President of BAM Federal Institute for Materials Research and Testing, and Professor at Humboldt University of Berlin, Germany.

A Study Following U.S. EPA Method 8081 Guidelines

Evaluation of strong and weak cation exchange columns and dependence of separation on mobile phase pH

This application note describes a solid phase extraction (SPE) protocol for the extraction of a range of mycotoxins from dried chili (pimiento) using ISOLUTE® Myco with LC-MS/MS analysis.

Whey is a by-product of the cheese-making process, and Whey Protein Isolate (WPI) is a dietary supplement and food ingredient created by separating components from milk. It contains a high percentage of pure protein and can be pure enough to be virtually lactose free, carbohydrate free, fat free, and cholesterol free. In this application note, a sample of WPI was characterized using the Viscotek TDAmax. The 4 main components in this mixture were separated and individually characterized.

This application note presents an example of how calorimetry aided the formulation development for ProX by providing insight into excipient-protein interactions. Polysorbate-80 and phenol are examined here as potential additives to the formulation buffer for ProX.

Work performed in conjunction with the Institut Pasteur, Paris, France Cations are specifically recognized by numerous proteins. Despite their small size, their specific interactions with highly charged residues allow them to induce significant conformational changes on their binding proteins.