November 2015 Issue of The Analytical Scientist

Peer reviews, Power Lists and the effects of heat (in GC and discussions).

Is the heat applied in gas chromatography-mass spectrometry really responsible for false results? And, if so, how often?

Using total reflection X-ray fluorescence for the non-destructive analysis of nuclear fuel oxides

Kickstarter technology is nothing new – but Clear Labs is making in-roads into something less common: kickstarter analytical science

Nanoporous gold helps ‘sieve out’ biological debris for fuss-free nucleic acid detection

A new DNA-based sensor shows promise for indirect detection of thallium

Online hyphenation of capillary electrophoresis and mass spectrometry is nearly 30 years old, but has been ignored in certain camps. It’s time to give CE-MS a chance.

The juxtaposition of simplicity through new technology with complexity in the chemistry keeps gas chromatographic method development exciting – despite GC being described by many as a “mature” technique. But are we still using packed-column thinking?

Can R&D organizations really afford to kill off analytical data that could be used for future decision-making? Perhaps it’s time to breathe life back into analytical data environments.

When it comes to measuring drugs in biological samples, what is needed, what is quantifiable – and what role should analytical scientists really be playing?

We ask an impossible question as 2015 comes to a close: which piece of literature stood out from the crowd

Just imagine how many analytical problems would be solved if we could increase the resolution of liquid chromatography (LC) from hundreds to thousands or perhaps a hundred thousand compounds?

Selecting “the paper of the year” is by definition subjective and very personal.

Capillary electrophoresis-mass spectrometry (CE-MS) appears to be caught in a dichotomy – proven success in some fields, skepticism in others.

Coupling whole column imaging detection to a mass spectrometer for protein structure characterization is fundamentally challenging. Could a relatively simple capillary cartridge system unlock the potential?

Sitting Down With… Detlef Günther, VP Research and Corporate Relations, and Professor for Trace Element and Micro Analysis, ETH Zürich, Switzerland.

Thin-layer chromatography’s ability to simply and inexpensively provide high-quality separations in parallel makes it the perfect partner for MALDI mass spectrometry

A growing target list, increasingly complex matrices, and the need for low limits of detection can make our field seem like an uphill treadmill.

Optimizing oxygen delivery improves stem cell treatment of peripheral artery disease.