App Notes

This application describes the use of ISOLUTE SLE+ for ultra-sensitive determination of 1,25 di-OH Vitamins D2 and D3.

In recent years a lot of research has been done on the medicinal use of Cannabis sativa. The shown method is suitable for confirmation of the cannabinoids CBN, CBD and THC by High-Performance Thin-Layer Chromatography coupled with a mass detector.

This application note demonstrates the advantages of the new diode array detector AZURA® DAD 2.1L.

In this AppNote, automated fractionation of lipid classes using solid phase extraction (SPE) is presented. The SPE fractions are concentrated and re-dissolved in small amounts of solvent, followed by LC-QTOF analysis.

This Application Note describes analysis of ppt-level PAHs in ambient air, using pumped sampling, thermal desorption, and gas chromatography. Using optimised sorbent sampling tubes, the method offers greater sensitivity compared to labour-intensive solvent-extraction protocols employed in many standardised methods.

Hydrophobic interaction chromatography (HIC), a technique commonly used for protein separation, is also used as an orthogonal method to size-exclusion and ion-exchange chromatography for the characterization of monoclonal antibodies and antibody-drug conjugates.

This application note describes the extraction of acidic, basic, and neutral drugs from urine for screening purposes using ISOLUTE® SLE+ supported liquid extraction plates prior to LC-MS/MS analysis.

Researchers from Prof. Guido Verbeck’s group at the University of North Texas (UNT) carried out analysis of drugs of abuse (DOA) and explosives using an ion trap GC-MS to compare results when using helium and hydrogen carrier and buffer gas.

The Dioxin family consists of 210 compounds, of which 17 contain the 2,3,7,8 pattern of chlorination.

The determination of the thermostability of PVC (also called dehydrochlorination test or DHC test) characterizes the stability of polyvinyl chloride or related chlorinated polymers against heat exposure.