App Notes

A high throughput process for the preparation and testing of samples for their surface tension using the epMotion 5075 Liquid handling platform and Kibron delta-8 tensiometer has been successfully developed and implemented at the Centre for Materials Discovery.

With the advent of the human genome era the molecular biology laboratory has once and for all changed from a small scale observatory into a semi-industrial, highly parallel environment with large numbers of samples and terabytes of processed data.

Talk of a helium crisis following the shortage of 2013 appears to have subsided thanks to increased worldwide production, with labs now readily able to obtain helium. This application note looks at what has happened over the last 2 years since the global helium shortage was the hot topic in GC.

In this study, optimized methods are presented for sample preparation and chiral chromatography for the LC/MS analysis of amphetamine and methamphetamine enantiomers in urine.

This application note illustrates the utility of organosilane enforced phases using expanded range of pH as a tool. This work also shows that consistent packing of mechanical and chemical stable enforced materials across different column sizes allows for straight forward scale-up.

As water content in gaseous matrices may interfere with synthesis reactions and also promotes corrosion of piping systems, the monitoring of residual water is essential. The application describes the sensitive, robust, and highly reliable Karl Fischer determination.

This application note presents a gradient method using a core shell column for the determination of various substances in Bourbon vanilla extracts as well as in natural and artificial vanilla flavors.

A rapid, accurate, and reproducible method was developed for high-throughput testing of nicotine, cotinine, trans-3'-hydroxycotinine, nornicotine, norcotinine, and anabasine in urine.

Dual-detection Gel Permeation Chromatography (GPC), also known as Size Exclusion Chromatography (SEC), provides an easy and effective way to measure the molar mass distribution and the amount of free, unbound polysaccharide of iron polysaccharide complexes.

Identifying the high- and low-concentration components of cheese aroma in a single analytical run is described, using a micro-chamber headspace sampling device, and analysis by thermal desorption (TD) with gas chromatography.