App Notes

Non-covalent or native mass spectrometry holds considerable promise for routine screening of ligand libraries for binding to a target protein. Direct infusion of a protein sample in the presence of ligand from an aqueous buffer, using nano-electrospray ionisation and ‘gentle’ MS source conditions, allows detection of the protein-ligand non-covalent complex.

In this application note, we measured the absorbance of a nutrient-dense juice blend comprising acai berries and other fruits.

The high concentration of phospholipids (PLs) in blood serum is a frequent limitation in metabolomic analysis based on mass spectrometric detection, mainly owing to their ionization suppression effects.

This application note describes a Solid Phase Extraction (SPE) protocol for the extraction of aflatoxin M1 (AM1) internally standardized with aflatoxin B2 (AB2) from infant formula using ISOLUTE® Myco SPE columns with LC MS/MS.

Methylglyoxal (MG) is an endogenous potent protein modifying agent, increased particularly in ageing, diabetes and kidney failure. It is an arginine-directed agent and often targets functionally important sites in proteins leading to inactivation.

During the last decade, the production and use of engineered nanomaterials (ENMs) have experienced a drastic increase, resulting in a potential risk of their release into the environment. Therefore, the study of their impact on the environment becomes crucial.

This study outlines the quantitation and characterization of element oxide nanoparticles (Al2O3, and CeO2) commonly used in the nanoelectronics and semiconductor fabrication industry for the chemical-mechanical planarization (CMP) of semiconductor surfaces.

With the increasing interest in nanoparticles, various ways of detecting and measuring them are being used.

Nanotechnology is an emerging and rapidly growing field whose dynamics and prospects pose many great challenges to scientists and engineers

Recent studies have shown that some nanoparticles may be harmful to humans.