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April 2016 Issue of The Analytical Scientist

Welcome to April’s issue! In Upfronts, we share a new approach for tackling ‘legal highs’ and find out why plucky pigeons are strapping on sensor vests for the good of humankind. Michele Lees asks if analytical scientists can outwit food fraudsters and three experts explain why pesticide analysis is still a hot topic. Power List heavyweight Jonathan Sweedler discusses analytical semantics and his search for answers in neuroscience, while Frank Bright talks about the amazing ‘toolbox’ of analytical science and what defines great research.

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Articles featured in this issue

Fields & Applications Clinical

The Translational Scientist

| Rich Whitworth

...the perfect companion to The Analytical Scientist.

Fields & Applications Spectroscopy

High Hopes

| Joanna Cummings

Can infrared absorption and Raman spectroscopy keep pace with clandestine chemists?

Techniques & Tools Technology

ZipChips and LIGHTNIRS

Two innovations that stood out from the crowd at Pittcon 2016

Techniques & Tools Environmental

Pigeon Patrol

| Joanna Cummings

Meet London’s first ever flock of pollution-monitoring birds

Techniques & Tools Spectroscopy

Ebb… Then Flow

| Joanna Cummings

The co-inventor of flow injection analysis is awarded the newly reinaugurated Talanta Medal

Techniques & Tools Proteomics

Million Peak Performance

| Joanna Cummings

Pioneering separations research gets the “STAMP” of approval

Techniques & Tools Technology

#ASAPbio

| Steven Lehotay

A single snappy hashtag questions the very nature of scientific publishing

Fields & Applications Forensics

Image of the Month

| Rich Whitworth

A close-up of cocaine distribution in washed hair strands

Techniques & Tools Food, Beverage & Agriculture

Outwitting Food Fraudsters

| Michèle Lees

Developing an effective strategy to combat food fraud can be challenging; it means thinking on your feet and staying ahead of the game.

Techniques & Tools Forensics

Forensics: The Next Generation

| Bruce McCord

How will modern genomics tools and other analytical breakthroughs drive forensic science?

Techniques & Tools Metabolomics & Lipidomics

The Trouble with Metabolomics

| Georgios Theodoridis

The pursuit of the metabolome may no longer be a novel field, but it remains the biggest analytical challenge.

Techniques & Tools Mass Spectrometry

Drifting into the Future with IMS

| Tim Causon

Why old technology or ideas still have a part to play when it comes to advancing analytical techniques.

Fields & Applications Microscopy

When Two Worlds Collide

| Jonathan Sweedler

What is the chemical nature of thought? What is memory? Why, over 2000 years since Aristotle first asked such questions, are we still searching?

Fields & Applications Liquid Chromatography

Guardians of Maximum Residue Limits

| Despo Louca, Magnus Jezussek, Sonja Masselter

Is pesticide residue analysis still a hot topic? Ahead of EPRW 2016 in Cyprus, current Chair – Despo Louca Christodoulou – and scientific organizing committee members Magnus Jezussek and Sonja Masselter discuss the importance of the field in challenging times.

Techniques & Tools Pharma & Biopharma

Language as Quality Control...

| Steven (Steve) Schultz

... or sonicate until the cockroaches disappear. When writing is central to the job of assuring health, safety, and quality, can you afford to be loose with language prone to misunderstanding? Why take a chance? Here are a few strategies to edit your written work for quality control.

Techniques & Tools Spectroscopy

Drawn to the Light

| Frank Bright

Sitting Down With... Frank Bright, Henry M. Woodburn Chair and SUNY Distinguished Professor, Department of Chemistry, University at Buffalo, New York.

Fields & Applications Liquid Chromatography

Determination of Lactose in Lactose-free Products Using HPAEC-PAD

| Mareike Margraf and Dr. Kate Monks

In many European countries, the limit of lactose in lactose-free labelled products has been lowered from 100 to 10 mg/100 g product in recent years (1).

Techniques & Tools Pharma & Biopharma

The Evolution of a Biocompatible Masterpiece - Thermo Scientific Vanquish Flex UHPLC

| Sponsored by Thermo Fisher Scientific

Meet the team responsible for realising the vision that led to the development of the Vanquish Flex.

Fields & Applications Mass Spectrometry

A Journey in Biotherapeutic Peptide Mapping

| Sponsored by Thermo Fisher Scientific

Learn about how the latest chromatography, mass spectrometry and software are accelerating confident decision making at Alexion Pharmaceuticals, Inc.

Techniques & Tools Pharma & Biopharma

Delivering for Biopharma

| Sponsored by Thermo Fisher Scientific

Althea have chosen to adopt new chromatography systems, designed and built for biotherapeutic characterization.

Techniques & Tools Sample Preparation

Viscotek SEC-MALS 20 to measure protein aggregation

| Sponsored by Malvern Panalytical

In this application note, a selection of proteins are separated using Size Exclusion Chromatograpghy (SEC). The molecular weights of their oligomers and aggregates are measured by SEC-MALS and the results discussed.

Techniques & Tools Sample Preparation

Case study: Effects of gamma-ray sterilization on high molecular weight

| Baljit Ghatora

A sample of PMMA was analysed by Size Exclusion Chromatography with Triple detection, before and after sterilization. Reduction in the molecular weight was shown to be firstly by cleaving the polymer at the branching points.

Techniques & Tools Sample Preparation

Assessing the effect of formulation composition on spidroin charge and stability

| Sponsored by Malvern Panalytical

This application note describes the use of a Zetasizer Nano ZSP to characterize the charge state of spidroins in different formulations. The earliest stages of spidroin aggregation in different formulations are then assessed using low-temperature synamic light scattering (DLS) thermal trend experiments.

Other issues of 2016