June 2014 Issue of The Analytical Scientist

When and where should we apply the concept of “just enough is best”?

In February 2001, scientists celebrated the initial sequencing of the human genome by two competing groups. Now, not one but two draft human proteomes form the next logical link in a chain.

While Bernard Kuster and his colleagues were compiling ProteomicsDB, a separate team of researchers at Johns Hopkins University, Baltimore, USA, and the Institute of Bioinformatics, Bangalore, India, tackled the challenge in a different way

Could a simple flower-shaped paper-based assay be the answer to an undiagnosed hepatitis C pandemic?

Teams in the UK, Finland, Spain, Switzerland and Italy join forces to tackle microfluidic-based assay development

Taking gas chromatography into the field has the potential to detect crop disease sooner

Nick Kim gifts us with his very analytical and amusing view of the world around us.

Surely, we’ve gone beyond thinking outside the box – the time has come to tell the box to respond to our thoughts.

Our capacity to generate data is unsurpassed, but how do we cope with the data deluge? It’s time to embrace data-driven discovery in biology and medicine.

The promise of cash generated from idle and surplus equipment sounds great. But how can you turn theoretical gains into practical benefits?

With so many modern teaching tools at our fingertips, shouldn’t we be making more of the time we spend with our students? I decided to “flip” my classroom in an attempt to answer that question.

The development of mass spectrometry is one of science’s great technology stories.

Is your “psychological immune system” preventing you from moving in positive new directions? By facing the hidden commitments that you harbor and challenging the assumptions that they are based upon, you really can modify your behavior. Here’s how.

Shell’s Pearl GTL brings in the big guns to tackle its vast data-handling requirements with an integrated laboratory information management system.

Sitting Down With… Salvatore Fanali, Head of the Capillary Electromigration and Chromatographic Methods Unit at the Institute of Chemical Methodologies, National Research Council (CNR), Monterotondo, Italy.

Impurity analysis with simultaneous determination of enantiomeric composition using the Agilent 1290 Infinity 2D-LC Solution

Over 10 years ago, the potential of two-dimensional liquid chromatography seemed obvious to me – so I built a system and never looked back.

This application note provides an example of how Archimedes can be used to detect and quantify the formation of protein sub-visible particles and the introduction of silicone oil droplets, in response to shear stress.