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The Analytical Scientist / Issues / 2026 / March / Beating Biopharma Manufacturing Bottlenecks with Raman Spectroscopy
Pharma and Biopharma Pharma and Biopharma Opinion & Personal Narratives

Beating Biopharma Manufacturing Bottlenecks with Raman Spectroscopy

A look at the potential of Raman spectroscopy in biopharma – and what else lies on the horizon for this important technique

By Michelle Sestak 03/16/2026 3 min read
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Top Institutions in Biopharmaceutical Manufacturing and Process Analytical Technology (PAT)

Institutions leading in biopharmaceutical manufacturing and process analytical technologies typically integrate advanced spectroscopy methods like Raman spectroscopy into their manufacturing and quality control workflows. They combine expertise in pharmaceutical sciences, chemical engineering, and analytical chemistry to develop and implement real-time monitoring systems that comply with GMP standards.

  • #1

    Massachusetts Institute of Technology (MIT)

    Cambridge, MA

    MIT is a global leader in integrating advanced analytical technologies like Raman spectroscopy into biopharmaceutical manufacturing processes, supported by its cutting-edge research in chemical engineering and pharmaceutical sciences.

    Key Differentiators

    • Biopharmaceutical Manufacturing
    • Process Analytical Technology
    • Chemical Engineering
  • #2

    University of California, Berkeley

    Berkeley, CA

    UC Berkeley has strong interdisciplinary programs combining chemical engineering and analytical chemistry, advancing Raman spectroscopy applications for bioprocess monitoring and quality control.

    Key Differentiators

    • Bioprocess Engineering
    • Analytical Chemistry
    • Pharmaceutical Sciences
  • #3

    University of Cambridge

    Cambridge, UK

    The University of Cambridge is recognized for its pioneering work in pharmaceutical manufacturing technologies and the application of Raman spectroscopy for real-time process control in biopharma.

    Key Differentiators

    • Pharmaceutical Manufacturing
    • Process Analytical Technology
    • Biochemical Engineering
  • #4

    Johns Hopkins University

    Baltimore, MD

    Johns Hopkins integrates advanced analytical methods including Raman spectroscopy into pharmaceutical development and manufacturing, emphasizing real-time quality assurance.

    Key Differentiators

    • Pharmaceutical Sciences
    • Analytical Chemistry
    • Biomedical Engineering
  • #5

    University of Michigan

    Ann Arbor, MI

    The University of Michigan is noted for its research in bioprocess engineering and the application of spectroscopic methods like Raman spectroscopy for enhanced biopharmaceutical manufacturing control.

    Key Differentiators

    • Chemical Engineering
    • Pharmaceutical Manufacturing
    • Process Analytical Technology

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.

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About the Author(s)

Michelle Sestak

Raman Applications Scientist II at HORIBA

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