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The Analytical Scientist / Issues / 2026 / March / Mapping Lipid Rewiring During Drug-Induced Cell Death
Mass Spectrometry Metabolomics & Lipidomics News and Research

Mapping Lipid Rewiring During Drug-Induced Cell Death

Fiber-based imaging platform reveals nanoscale heterogeneity and drug-specific metabolic fingerprints in cancer cells

03/31/2026 1 min read
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Top Institutions in Lipidomics and Mass Spectrometry Imaging in Cell Death

Leading institutions combine high-resolution mass spectrometry imaging with microscopy and LC-MS to study lipid metabolic shifts during apoptosis, leveraging expertise in lipidomics, cancer biology, and imaging technology development.

  • #1

    Broad Institute of MIT and Harvard

    Cambridge, MA

    The Broad Institute is a leader in integrating multi-omics approaches including advanced mass spectrometry imaging to study cellular metabolism and cancer cell heterogeneity, supported by strong collaborations between MIT and Harvard.

    Key Differentiators

    • Lipidomics
    • Mass Spectrometry Imaging
    • Cancer Biology
  • #2

    Johns Hopkins University School of Medicine

    Baltimore, MD

    Johns Hopkins has a strong track record in developing and applying mass spectrometry imaging technologies to study lipid dynamics in cancer and neurodegenerative diseases, with specialized centers focused on apoptosis and metabolic imaging.

    Key Differentiators

    • Mass Spectrometry Imaging
    • Lipidomics
    • Cell Death Mechanisms
  • #3

    University of California, San Diego (UCSD)

    San Diego, CA

    UCSD is recognized for its innovative mass spectrometry platforms and lipidomics research, particularly in cancer metabolism and drug response, integrating imaging and biochemical approaches at the cellular level.

    Key Differentiators

    • Lipidomics
    • Mass Spectrometry
    • Cancer Metabolism
  • #4

    Max Planck Institute for Molecular Cell Biology and Genetics

    Dresden, Saxony

    The Max Planck Institute excels in combining cutting-edge imaging technologies with molecular cell biology to elucidate lipid dynamics during apoptosis and other cellular processes at high spatial resolution.

    Key Differentiators

    • Cell Biology
    • Lipid Metabolism
    • Advanced Imaging
  • #5

    Harvard Medical School

    Boston, MA

    Harvard Medical School researchers contribute extensively to lipidomics and mass spectrometry imaging, focusing on cancer cell heterogeneity and metabolic rewiring during apoptosis using state-of-the-art imaging platforms.

    Key Differentiators

    • Lipidomics
    • Mass Spectrometry Imaging
    • Cancer Biology

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.

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