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Techniques & Tools Technology, Proteomics, Genomics & DNA Analysis, Mass Spectrometry, Pharma & Biopharma, Liquid Chromatography, Capillary Electrophoresis

The Tools of Proteomics

Just as proteins are the third component in the flow of genetic information after DNA and RNA, so proteomics represents the third challenge temporally in the comprehensive analysis of living systems, after genomics and transcriptomics. It is also the most complex of these challenges. Proteins are much more diverse and difficult to quantitate than nucleic acids, and unlike DNA, their expression varies in both time and space. 

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About the Authors

Norm Dovichi

Norm Dovichi’s postdoctoral fellowship at Los Alamos Scientific Lab introduced the concept of single molecule detection, leading to the development of a capillary array DNA sequencer that became the workhorse tool used in the human genome project.


Amanda Hummon

Amanda Hummon is Huisking Foundation Inc. Associate Professor at University of Notre Dame, Indianapolis, USA. The interests of the Hummon Research Group lie at the intersection of analytical chemistry and chemical biology, with a focus on cancer biology. They develop high-throughput methods to evaluate the proteome and transcriptome in cancer cells.

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